Korean J Anesthesiol.  2012 Sep;63(3):260-262. 10.4097/kjae.2012.63.3.260.

Anaphylaxis induced by hydroxyethyl starch during general anesthesia: A case report

• Kim HJ
• Kim SY
• Oh MJ
• Kim JM

• KMID: 2236277
• DOI: http://doi.org/10.4097/kjae.2012.63.3.260

Abstract

Hydroxyethyl starch (HES) solutions are synthetic non-protein colloid solutions used to treat hypovolemia. However, their use is not free from the risk of allergic reactions. A 42-year-old male was scheduled to undergo aortic-iliac-femoral bypass surgery for the treatment of arteriosclerosis obliterans. He had no history of allergy. Two hours after the start of surgery, and within minutes after HES administration, facial erythema, hypotension and bronchospasm developed. HES infusion was discontinued under the estimation of anaphylaxis. The patient received phenylephrine, ephedrine, diphenhydramine and hydrocortisone with hydration. After restoration of vital signs, surgery was performed without complications.

Keyword

Anaphylaxis; Bronchospasm; Erythema; Hydroxyethyl starch

MeSH Terms

Adult
Anaphylaxis
Arteriosclerosis Obliterans
Bronchial Spasm
Colloids
Diphenhydramine
Ephedrine
Erythema
Hetastarch
Humans
Hydrocortisone
Hypersensitivity
Hypotension
Hypovolemia
Male
Phenylephrine
Vital Signs
Colloids
Diphenhydramine
Ephedrine
Hetastarch
Hydrocortisone
Phenylephrine