Korean J Asthma Allergy Clin Immunol.  2008 Sep;28(3):214-219.

Association between Nasal Eosinophil Count and Other Clinical Indices in Children with Chronic Nasal Symptoms

Abstract

BACKGROUND: Nasal eosinophil count is known to be associated with allergen-specific IgE reaction, serum total IgE level, and blood eosinophil count in patients with allergic rhinitis.
OBJECTIVE
To examine the association between nasal eosinophil count and other clinical indices in children with chronic nasal symptoms. METHOD: The medical records were reviewed retrospectively. The smears of nasal swabs were examined under the light microscope for nasal eosinophil count. The statistical analysis was done in correlation to nasal eosinophil count and clinical indices. RESULT: The number of patients with a history of allergic diseases other than allergic rhinitis and positive reactions to serum allergen-specific IgE antibodies in the considerable group (52.9% and 92.0%) was significantly higher than those in the absent group (28.8% and 55.1%) (P<0.05). The number of patients with nasal symptom duration of less than 3 weeks in the absent group (31.2%) was significantly higher than that in the other groups (P<0.05). Blood eosinophil counts were significantly higher in the considerable group (491.2+/-264.0/mm3) than those in the absent group (310.2+/-293.7/mm3) (P<0.05).
CONCLUSION
Nasal eosinophil counts significantly correlated with a history of other allergic diseases, duration of nasal symptoms, positive reactions to serum allergen- specific IgE antibodies and blood eosinophil count.

MeSH Terms

Antibodies
Child
Eosinophils
Humans
Immunoglobulin E
Light
Medical Records
Nose
Retrospective Studies
Rhinitis
Rhinitis, Allergic, Perennial
Antibodies
Immunoglobulin E