Korean J Dermatol.  1989 Oct;27(5):582-588.

A Case of Persistent Grover's Disease

• Kim KH
• Kim YC
• Lee AY
• Cho KH
• Lee YS

Abstract

We herein presented a case of persistent variant of Grovers disease in a 83-year old male. He had a rather extensive eruption of erythematous scaly papules, which had been profusely grouped but discretely distributed over 2 years or more. The histopathologic findings of two lesions in the same patient revealed mixture of various histologic patterns, patterns resembling Dariers disease, pemphigus vulgaris, Hailey-Hailey disease and spongiosis. The ultrastructural findings of Darier pattern should be essentially similar to those of Dariers disease and also be common to those observed in the early stages of other causes of focal acantholytic dyskeratosis. The patient had been treated with topical and intralesional steroid and oral 13-cis-isotretinoin, however, the lesions had been persisted only with partial improvement of clinical appearance and reduction of pruritus.

Keyword

Focal acantholytic dyskeratosis; Grovers disease; Persistent variant

MeSH Terms

Aged, 80 and over
Darier Disease
Humans
Male
Pemphigus
Pemphigus, Benign Familial
Pruritus