Korean J Dermatol.  2002 Aug;40(8):1004-1006.

A Case of Transient Acantholytic Dermatosis

Affiliations
  • 1Department of Dermatology, College of Medicine, Inha University, Incheon, Korea. garden@inha.ac.kr

Abstract

Transient acantholytic dermatosis was first described by Grover in 1970. It is characterized by pruritic, discrete papules and papulovesicles distributed mainly on the trunk. The histologic hallmark of the disorder is focal acantholysis, several patterns of which have been described. The etiologic factors and pathogenesis remain unclear. We report a 45-year-old male patient with multiple severely pruritic, discrete papules and papulovesicles on the trunk. There were no oral cavity, palm and sole involvement. Histopathologic findings revealed epidermal acanthosis, acantholysis and hyperkeratosis with suprabasal splits. He showed good response to topical steroid and oral antihistamine.

Keyword

Transient acantholytic dermatosis; Grover; Acantholysis

MeSH Terms

Acantholysis
Humans
Male
Middle Aged
Mouth
Skin Diseases*
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