Korean J Dermatol.
2016 Jul;54(6):472-476.
Grover Disease Showing Features of Nonspecific Eczematous Dermatosis
- Affiliations
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- 1Department of Dermatology, VHS Medical Center, Seoul, Korea. zooooz@hanmail.net
- 2Department of Pathology, College of Medicine, Kyung Hee University, Seoul, Korea.
Abstract
- Grover disease (GD), also referred to as transient or persistent acantholytic dermatosis, is an acquired pruritic papular or papulovesicular eruption characterized histopathologically by focal acantholysis and dyskeratosis. Because GD resembles several generalized papular diseases, the diagnosis of GD is a clinical challenge, particularly when dermatologists meet patients without papular eruptions. We experienced two elderly men showing eczematoid plaques with severe pruritus on their backs. Histopathological examinations revealed a focal acantholysis, spongiosis, and dyskeratosis, a pattern consistent with GD. We report two cases of GD with clinical features of nonspecific eczematous dermatosis.
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