Korean J Dermatol.
2000 Nov;38(11):1561-1563.
A Case of Darier's disease with preceding lesions of palm and sole
- Affiliations
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- 1Department of Dermatology, College of Medicine, Korea University Seoul, Korea.
Abstract
- Darier's disease is an autosomal dominant disorder with altered keratinization of the epidermis, but many cases are sporadic and presumably represent new mutation. Multiple discrete, keratotic, asymptomatic or mild pruritic papules are present at not only the seborrheic areas but also oral mucosa, palm and sole. The histologic characteristic changes in Darier's disease are formation of corps ronds and grains, suprabasal acantholysis and villi. We experienced a case of Darier's disease with preceding lesions of palm and sole, so reported this case with literature review.
