Korean Circ J.  1984 Jun;14(1):151-156. 10.4070/kcj.1984.14.1.151.

Clinical Effect of Nicardipine(Perdipine(R)) on Cerebrovascular Diseases

• Choi SJ
• Yoo WS

• KMID: 2229822
• DOI: http://doi.org/10.4070/kcj.1984.14.1.151

Abstract

Twenty-five patients with cerebrovascular diseases were administered Nicardipine, a calcium antagonist, in daily dose of 60 mg per orally for 8-12 weeks during the year of 1983, to evaluate the efficacy of the drugs clinically. The following results were obtained. 1) General improvement rating was 80%. 2) Marked improvement(88%) were noted in subjective symptoms, especially of tinnitus, paresthesia and headache. significant improvement were noted in psychiatric(74%) and neurologic(71%) symptoms e.g disturbance of sleep, emotion, memory, speech, swallowing and muscle power. 3) In 13 hypertensive patients, average blood pressure lowered from 163/96 to 138/83 mmHg in 4 weeks and maintained thereafter. 4) major adverse effect was facial flushing, noted in 4 patients(16%), which were transient and mild and allowed to contiume medication.

MeSH Terms

Blood Pressure
Calcium
Deglutition
Flushing
Headache
Humans
Memory
Nicardipine
Paresthesia
Tinnitus
Calcium
Nicardipine