Korean J Crit Care Med.  2009 Dec;24(3):176-180. 10.4266/kjccm.2009.24.3.176.

Extreme Drug Resistant Acinetobacter Nosocomial Ventilator-Associated Pneumonia Treated Successfully with Tigecycline and Amikacin in Intensive Care Unit: A Case Report

Affiliations
  • 1Division of Pulmonary and Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
  • 2Seoul Medical Center, Seoul, Korea.
  • 3Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. drchung@skku.edu

Abstract

Infections due to multidrug resistant Acinetobacter baumannii have become a challenging problem in intensive care units. Tigecycline is a derivative of minocyline, and has provided new hope for the treatment of multidrug-resistant A. baumannii infections. Because isolates showing reduced susceptibility to minocycline or tigecycline have emerged in many countries, empirical combination therapy has become common practice to treat patients infected with extreme drug-resistant A. baumannii. Herein we report a case of extreme drug-resistant A. baumannii infection successfully treated with tigecycline and amikacin.

Keyword

acinetobacter; amikacin; tigecycline; ventilator-associated pneumonia

MeSH Terms

Acinetobacter
Acinetobacter baumannii
Amikacin
Humans
Critical Care
Intensive Care Units
Minocycline
Pneumonia, Ventilator-Associated
Amikacin
Minocycline
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