Korean J Crit Care Med.  2012 Aug;27(3):173-178. 10.4266/kjccm.2012.27.3.173.

Anesthetic Management of Whole-Lung Lavage Using Propofol-Remifentanil in a Patient with Pulmonary Alveolar Proteinosis

• Lee JH
• Chung CJ
• Oh JN
• Ko BJ
• Choi SR

• KMID: 2227965
• DOI: http://doi.org/10.4266/kjccm.2012.27.3.173

Abstract

Pulmonary alveolar proteinosis (PAP) is characterized by the progressive accumulation of phospholipids and proteins within the alveolar sacs without producing an inflammatory response. Whole-lung lavage (WLL) is performed as the standard therapy for this disease because it serves to wash out the proteinaceous material from the alveoli. In this case, we performed sequential WLL using propofol-remifentanil, which is not related to hypoxic pulmonary vasoconstriction during one-lung ventilation. The patient's symptoms and radiologic findings showed improvement without the occurrence of any specific complications. Therefore, we report a case of anesthetic management of WLL performed repeatedly for a patient with recurrent PAP.

Keyword

hypoxic pulmonary vasoconstriction; propofol-remifentanil; pulmonary alveolar proteinosis; whole-lung lavage

MeSH Terms

Humans
One-Lung Ventilation
Phospholipids
Proteins
Pulmonary Alveolar Proteinosis
Therapeutic Irrigation
Vasoconstriction
Phospholipids
Proteins