Korean Circ J.  2007 Dec;37(12):609-615. 10.4070/kcj.2007.37.12.609.

Risk Factors for Predicting New-Onset Atrial Fibrillation in Persons Who Received Health Screening Tests

Affiliations
  • 1Division of Cardiology, Department of Medicine, Cardiac and Vascular Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. yk.on@samsung.com
  • 2Division of Cardiology, Department of Medicine, Dongsuwon Hospital, Suwon, Korea.

Abstract

BACKGROUND AND OBJECTIVES: Atrial fibrillation (AF) is the most common significant arrhythmia in the general population, and it is associated with increased cardiovascular morbidity and mortality. The incidence of and the risk factors for new-onset AF have not been well evaluated in Koreans.
SUBJECTS AND METHODS
We retrospectively analyzed 16,568 adults (median age 49 years, 10,685 males and 5,883 females) who had repeatedly received screening tests for general health at the Health Promotion Center, Samsung Medical Center in Korea between March, 2001 and June, 2006 (mean follow up duration: 44 months).
RESULTS
Sixty one cases had new-onset AF noted on the electrocardiogram (ECG). On the univariate analysis, age, male gender, a history of coronary artery disease and taking hypertension medication, the waist circumference, body mass index, fasting glucose, hemoglobin A1c, fibrinogen, and left atrium enlargement seen on ECG at baseline were significantly associated with new-onset AF. After multivariable adjustment, the independent risk factors for predicting new-onset AF were male gender [odds ratio (OR): 3.356, 95% confidence interval (CI): 1.168-9.643, p=0.025] and a history of coronary artery disease (OR: 4.657, 95% CI: 1.703-12.737, p=0.003).
CONCLUSION
The risk factors for predicting new-onset AF in persons who received general health screening tests were male gender and a history of coronary artery disease.

Keyword

Atrial fibrillation; Risk factor

MeSH Terms

Adult
Arrhythmias, Cardiac
Atrial Fibrillation*
Body Mass Index
Coronary Artery Disease
Electrocardiography
Fasting
Fibrinogen
Follow-Up Studies
Glucose
Health Promotion
Heart Atria
Humans
Hypertension
Incidence
Korea
Male
Mass Screening*
Mortality
Retrospective Studies
Risk Factors*
Waist Circumference
Fibrinogen
Glucose

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