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Prevalence, Treatment Status, and Comorbidities of Hyperthyroidism in Korea from 2003 to 2018: A Nationwide Population Study

Ahn HY, Cho SW, Lee MY, Park YJ, Koo BS, Chang HS, Yi KH

Background: This study aimed to investigate the changes of incidence and treatment of choice for hyperthyroidism from 2003 to 2018 and explore the treatment-related complications and concomitant comorbidities in South...
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Enhanced Bone Formation by Rapidly Formed Bony Wall over the Bone Defect Using Dual Growth Factors

Park J, Jung N, Lee DJ, Oh S, Kim S, Cho SW, Kim JE, Moon HS, Park YB

BACKGROUND: In guided bone regeneration (GBR), there are various problems that occur in the bone defect after the wound healing period. This study aimed to investigate the enhancement of the...
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Prevalence and Clinical Implications of Lateral Wall Dehiscence in the Sphenoid Sinus: Sternberg’s Canal

Kang SH, Huh G, Kim M, Bae YJ, Won TB, Kim JW, Rhee CS, Cho SW

Background and Objectives: Sternberg’s canal is known to result from incomplete fusion of bony compartments constituting the sphenoid bone during the developmental process. This study aimed to evaluate the prevalence...
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Pharmacologic Activation of Angiotensin-Converting Enzyme II Alleviates Diabetic Cardiomyopathy in db/db Mice by Reducing Reactive Oxidative Stress

Kim D, Jeong W, Kim Y, Lee J, Cho SW, Oh CM, Park R

Background: Diabetes mellitus is one of the most common chronic diseases worldwide, and cardiovascular disease is the leading cause of morbidity and mortality in diabetic patients. Diabetic cardiomyopathy (DCM) is...
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Intestinal Peyer’s Patches: Structure, Function, and In Vitro Modeling

Park JI, Cho SW, Kang JH, Park TE

BACKGOUND: Considering the important role of the Peyer’s patches (PPs) in gut immune balance, understanding of the detailed mechanisms that control and regulate the antigens in PPs can facilitate the...
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Associations Between Systemic Inflammatory Markers Based on Blood Cells and Polysomnographic Factors in Obstructive Sleep Apnea

Kim M, Cho SW, Won TB, Rhee CS, Kim JW

Objectives. Systemic inflammation plays a key role in the pathogenesis of obstructive sleep apnea (OSA); however, easy-to-use methods to evaluate the severity of systemic inflammation have yet to be developed....
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Sphenoid Bone Determines the Curvature of the Cranial Vault in Postnatal Skull Development in C57BL/6 Mice

Adasooriya D, Kyeong M, Cho SW

Background: The skull is a complex structure formed by the craniofacial bones’ elaborate organization. The growth pattern in each craniofacial bone of the postnatal skull has been presented in wild-type...
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Big Data Research in the Field of Endocrine Diseases Using the Korean National Health Information Database

Cho SW, Kim JH, Choi HS, Ahn HY, Kim MK, Rhee EJ

The Korean National Health Information Database (NHID) contains big data combining information obtained from the National Health Insurance Service and health examinations. Data are provided in the form of a...
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Risk factors for prolonged hospitalization and delayed treatment completion after laparoscopic appendectomy in patients with uncomplicated acute appendicitis

Shin J, Ihn MH, Kim KS, Kim SH, Lee J, Yun S, Cho SW

Purpose: We sought to identify the risk factors for prolonged hospitalization and delayed treatment completion after laparoscopic appendectomy in patients with uncomplicated acute appendicitis. Methods: The study retrospectively analyzed 497 patients...
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BRAFV600E Mutation Enhances Estrogen-Induced Metastatic Potential of Thyroid Cancer by Regulating the Expression of Estrogen Receptors

Kim M, Kim Sj, Ha SY, Xu Z, Han Y, Jee HG, Cho SW, Park YJ, Lee KE

Background: Cross-talk between mitogen-activated protein kinase and estrogen has been reported; however, the role of BRAFV600E in the estrogen responsiveness of thyroid cancer is unknown. We elucidated the effect of...
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Mitochondrial energy metabolic transcriptome profiles during cardiac differentiation from mouse and human pluripotent stem cells

Cho SW, Kim HK, Sung JH, Kim Y, Kim JH, Han J

Simultaneous myofibril and mitochondrial development is crucial for the cardiac differentiation of pluripotent stem cells (PSCs). Specifically, mitochondrial energy metabolism (MEM) development in cardiomyocytes is essential for the beating function....
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Clinical Outcomes of Repeated Radioactive Iodine Therapy for Graves’ Disease

Kim MJ, Cho SW, Kim YA, Choi HS, Park YJ, Park DJ, Cho BY

Background: Radioactive iodine (RAI) therapy is a successful therapeutic modality for Graves’ disease. However, RAI therapy can fail, and RAI therapy after antithyroid drugs (ATDs) has a lower remission rate....
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Evaluation and Management of Bone Health in Patients with Thyroid Diseases: a Position Statement from the Korean Thyroid Association

Hong AR, Ahn HY, Kim BK, Ahn SH, Park SY, Kim MH, Lee J, Cho SW, Kang HC

Thyroid hormones have an important physiological role in maintaining adult bone structure and strength. Therefore, thyroid dysfunction is inevitably associated with various degrees of skeletal consequences. Endogenous overt hyperthyroidism is...
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Simultaneous Reconstruction of a Subtotal Maxillectomy and Columella Deficit using Radial Forearm and Preauricular Free Flaps

Yoon T, Eun S, Cho SW, Rhee CS

Reconstruction of subtotal maxillectomy defects with columella deficit is challenging. We report a unique case of facial reconstruction using a free radial forearm flap and a free preauricular flap for...
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Development of High-Intensity Focused Ultrasound Therapy for Inferior Turbinate Hypertrophy

Kim JK, Cho SW, Kim H, Jo SC, Kim HG, Won TB, Kim JW, Lim JH, Rhee CS

Objectives. Inferior turbinate (IT) hypertrophy is the main cause of chronic nasal obstruction. We developed a high-intensity focused ultrasound (HIFU) ablation device to treat patients with IT hypertrophy. Methods. First, computed...
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Protocol for a Korean Multicenter Prospective Cohort Study of Active Surveillance or Surgery (KoMPASS) in Papillary Thyroid Microcarcinoma

Jeon MJ, Kang YE, Moon JH, Lim DJ, Lee CY, Lee YS, Kim SW, Kim MH, Kim BH, Kang HC, Shong M, Cho SW, Kim WB

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10-Year Fracture Risk in Postmenopausal Women with Osteopenia and Osteoporosis in South Korea

Baek YH, Cho SW, Jeong HE, Kim JH, Hwang Y, Lange JL, Shin JY

Background: In South Korea, women aged 66 years are eligible for complimentary bone mineral density (BMD) screening via the National Screening Program for Transitional Ages. We aimed to evaluate the...
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2021 Korean Thyroid Imaging Reporting and Data System and Imaging-Based Management of Thyroid Nodules: Korean Society of Thyroid Radiology Consensus Statement and Recommendations

Ha EJ, Chung SR, Na DG, Ahn HS, Chung J, Lee JY, Park JS, Yoo RE, Baek JH, Baek SM, Cho SW, Choi YJ, Hahn SY, Jung SL, Kim Jh, Kim SK, Kim SJ, Lee CY, Lee HK, Lee JH, Lee YH, Lim HK, Shin JH, Sim JS, Sung JY, Yoon JH, Choi M

Incidental thyroid nodules are commonly detected on ultrasonography (US). This has contributed to the rapidly rising incidence of low-risk papillary thyroid carcinoma over the last 20 years. The appropriate diagnosis...
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Comparison of Korean vs. American Thyroid Imaging Reporting and Data System in Malignancy Risk Assessment of Indeterminate Thyroid Nodules

Kang S, Kwon SK, Choi HS, Kim MJ, Park YJ, Park DJ, Cho SW

Background: The management of cytologically indeterminate thyroid nodules is challenging for clinicians. This study aimed to compare the diagnostic performance of the Korean Thyroid Imaging Reporting and Data Systems (K-TIRADS)...
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Association between Iodine Intake, Thyroid Function, and Papillary Thyroid Cancer: A Case-Control Study

Kim K, Cho SW, Park YJ, Lee KE, Lee DW, Park SK

Background: This study aimed to assess the effects of iodine intake, thyroid function, and their combined effect on the risk of papillary thyroid cancer (PTC) and papillary thyroid microcarcinoma (PTMC). Methods:...
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