Korean Circ J.  2008 Feb;38(2):87-94. 10.4070/kcj.2008.38.2.87.

Full Metal Jackets (> or =60 mm) of Drug-Eluting Stents: Short- and Long-term Clinical and Angiographic Outcomes

• Lee SH
• Chae JK
• Lee KH
• Lee SR
• Rhee KS
• Kim WH
• Ko JK

• KMID: 2225842
• DOI: http://doi.org/10.4070/kcj.2008.38.2.87

Abstract

BACKGROUND AND OBJECTIVES
Drug-eluting stents (DES) are effective for the maintenance of patency in patients with various complex coronary artery diseases. We investigated the efficacy of full metal jackets (FMJs,> or =60 mm) using overlapping DES for very long coronary lesions.
SUBJECTS AND METHODS
The medical records and angiographic data of ninety-nine patients, and 100 FMJs that were implanted at Chonbuk National University Hospital since March 2003, were analyzed.
RESULTS
The mean age was 63+/-10 years and median follow-up period was 17.0 months. The mean lesion length was 57.7+/-10.8 mm, the mean number of implanted DES for FMJ was 2.2+/-0.5, and the mean length of the FMJ was 68.5+/-11.4 mm. Thirty percent of the lesions were the culprits of acute myocardial infarction and 22% were chronic total occlusive lesions. The procedural success rate was 98%. Triple antiplatelet agents were prescribed for 37.4% of the patients and the mean duration of clopidogrel use was 11.9+/-5.7 months. Overall major adverse cardiac events developed in 10% of patients. One patient died of probable stent thrombosis by the Academic Research Consortium definition. Follow-up coronary angiography was performed in 69% of cases. Binary restenosis was documented in 9 lesions (13.0%) and five FMJs (7.2%) were revascularized. Stent fractures were detected in four FMJs (5.8%).
CONCLUSION
Although FMJs using DES may be regarded as a relatively safe and effective therapeutic approach for diffuse long coronary lesions, longer-term follow-up data with a larger population is needed to establish safety including special consideration for strategy of antiplatelet therapy.

Keyword

Drug-Eluting stents; Percutaneous transluminal coronary angioplasty

MeSH Terms

Angioplasty, Balloon, Coronary
Coronary Angiography
Coronary Artery Disease
Drug-Eluting Stents
Follow-Up Studies
Humans
Medical Records
Myocardial Infarction
Platelet Aggregation Inhibitors
Stents
Thrombosis
Ticlopidine
Platelet Aggregation Inhibitors
Ticlopidine

Figure

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  Fig. 1 Kaplan-Meier cardiac event-free survival curve.

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