Korean J Clin Microbiol.  2005 Oct;8(2):194-197.

A Case of Fatal Scedosporium prolificans Fungemia in a Patient with Acute Myeloid Leukemia

Affiliations
  • 1Department of Laboratory Medicine, Korea University, College of Medicine, Seoul, Korea. cklee@korea.ac.kr

Abstract

Scedosporium prolificans is a saprophytic fungus widespread in the environment. It has become an emerging pathogen in recent years causing disseminated infections, especially in profoundly neutropenic immunocompromised patients. We report a case of fatal Scedosporium fungemia in a 45 year old female with acute myeloid leukemia in relapse. She received salvage chemotherapy and antibiotic treatment, and was neutropenic with relapsing fever. S. prolificans was isolated repeatedly from the aerobic bottles on the second day of two successive blood cultures. Amphotercin B was started; however, the patient expired the next day.

Keyword

Scedosporium prolificans; Fungemia; Immunocompromised

MeSH Terms

Drug Therapy
Female
Fungemia*
Fungi
Humans
Immunocompromised Host
Leukemia, Myeloid, Acute*
Middle Aged
Recurrence
Relapsing Fever
Scedosporium*
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