Korean J Med.  2015 Nov;89(5):581-584. 10.3904/kjm.2015.89.5.581.

Myeloid Sarcoma of Peritoneum in Acute Myeloid Leukemia Patient with Inversion of Chromosome 16

• Kim JY
• Park BK
• Bae SH
• Ryoo HM
• Sung WJ
• Lee AJ

• KMID: 2268962
• DOI: http://doi.org/10.3904/kjm.2015.89.5.581

Abstract

Myeloid sarcoma is an extramedullary myeloid neoplasm that usually involves the skin, soft tissues, and lymph nodes. Myeloid sarcoma is found in 2.5-9.1% of acute myeloid leukemia patients, usually those with t (8;21), while inv (16) is rarely associated with myeloid sarcoma. Consequently, little is known of the characteristics and incidence of inv (16) in myeloid sarcoma. Myeloid sarcoma in acute myeloid leukemia patients with inv (16) is most often found in the abdominal lesions; the intestinal tract is involved most commonly, in the form of a mass. Here, we report an unusual myeloid sarcoma presenting as peritoneal carcinomatosis in acute myeloid leukemia with inv (16) that appeared to be ascites.

Keyword

Sarcoma, Myeloid; Leukemia, Myeloid, Acute; Inv (16) fusion protein, Human

MeSH Terms

Ascites
Carcinoma
Chromosomes, Human, Pair 16*
Humans
Incidence
Leukemia, Myeloid, Acute*
Lymph Nodes
Peritoneum*
Sarcoma, Myeloid*
Skin