Kidney Res Clin Pract.  2012 Sep;31(3):192-195.

Laparoscopic biopsy-proven lupus nephritis in autosomal dominant polycystic kidney disease

Affiliations
  • 1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. mednep@snubh.org
  • 2Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.

Abstract

A 48-year-old woman with autosomal dominant polycystic kidney disease (ADPKD) presented with generalized edema and arthralgia. She showed evidences of acute glomerulonephritis including nephrotic-ranged proteinuria. Because her serologic test results were consistent with those for systemic lupus erythematosus (SLE), we performed laparoscopic renal biopsy that confirmed World Health Organization (WHO) class IV lupus nephritis. She was treated with steroids and intravenous cyclophosphamide pulse therapy and eventually started hemodialysis 8 years after the lupus nephritis was diagnosed. To our knowledge, this is the first case wherein a patient with ADPKD underwent a laparoscopic biopsy for diagnosing lupus nephritis.

Keyword

Laparoscopy; Lupus nephritis; Polycystic kidney disease

MeSH Terms

Arthralgia
Biopsy
Cyclophosphamide
Edema
Female
Glomerulonephritis
Humans
Laparoscopy
Lupus Erythematosus, Systemic
Lupus Nephritis
Middle Aged
Polycystic Kidney Diseases
Polycystic Kidney, Autosomal Dominant
Proteinuria
Renal Dialysis
Serologic Tests
Steroids
World Health Organization
Cyclophosphamide
Steroids
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