J Rheum Dis.  2011 Sep;18(3):208-211. 10.4078/jrd.2011.18.3.208.

A Case of Ankylosing Spondylitis Associated with Turner's Syndrome

• Kim YS
• Jeong YJ
• Kim HS

• KMID: 2223152
• DOI: http://doi.org/10.4078/jrd.2011.18.3.208

Abstract

Turner's syndrome (TS) is a chromosomal disorder where phenotypic females have either a missing chromosome (45 XO) or a structural aberration in one of the chromosomes. Previous studies have suggested that women with TS may be at increased risk of several autoimmune diseases, such as Hashimoto thyroiditis, celiac disease, Crohn's disease, ulcerative colitis, juvenile rheumatoid arthritis, and vitiligo. Although a high risk has been documented for autoimmune diseases in TS, there is only one case reporting the relationship between TS and ankylosing spondylitis (AS) in the literature. Herein, we present an unusual case of AS associated with TS.

Keyword

Ankylosing spondylitis; Turner's syndrome

MeSH Terms

Arthritis, Juvenile Rheumatoid
Autoimmune Diseases
Celiac Disease
Chromosome Disorders
Colitis, Ulcerative
Crohn Disease
Female
Hashimoto Disease
Humans
Spondylitis, Ankylosing
Turner Syndrome
Vitiligo

Figure

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  Figure 1. In chromosome anaylsis, karyotype of the patient was 45,XO (arrow).

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  Figure 2. Oblique views of sacroiliac joints show minimal subcortical erosions, subchondral sclerosis, and indistinctness of joint space at the bilateral sacroiliac joint.

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  Figure 3. (A) Oblique coronal T2-weighted magnetic resonance image (MRI) shows multiple subcortical erosions, joint space widening in the right sacroiliac joint (white arrows) and bone marrow edema in the left sacroiliac joint (black arrow). (B) Oblique coronal fat-suppressed T2-weighted MRI shows an irregular margin, and subchondral sclerosis in the bilateral sacroiliac joints (black arrows).

Reference

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