Korean J Med.
2016 Jun;90(6):554-558. 10.3904/kjm.2016.90.6.554.
Acquired Pure Red Cell Aplasia following Autoimmune Hemolytic Anemia in Systemic Lupus Erythematosus
- Affiliations
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- 1Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. woncomet@catholic.ac.kr
- 2Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
- KMID: 2218782
- DOI: http://doi.org/10.3904/kjm.2016.90.6.554
Abstract
- Pure red cell aplasia (PRCA) is a rare hematological disorder characterized by severe normochromic normocytic anemia and reticulocytopenia due to erythroid progenitor depletion in an otherwise normal bone marrow. Autoimmune hemolytic anemia (AIHA) is caused by autoantibodies directed against red blood cells with normocytic or macrocytic anemia with reticulocytosis. Both diseases can develop in conjunction with various underlying diseases, such as immunological disorders. Although rare, there have been a few cases of AIHA followed by PRCA. Here, we report a patient who developed PRCA following AIHA and was later diagnosed with systemic lupus erythematosus.
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