J Korean Ophthalmol Soc.  2015 Nov;56(11):1767-1776. 10.3341/jkos.2015.56.11.1767.

Thickness in Ganglion Cell-Inner Plexiform Layer on Spectral-Domain Optical Coherence Tomography after Cataract Surgery

• Shin WB
• Jeong HK
• Kim JH
• Lee JM
• Hong SM
• Kim CY
• Seong GJ
• Park KS

• KMID: 2214186
• DOI: http://doi.org/10.3341/jkos.2015.56.11.1767

Abstract

PURPOSE
To assess changes in ganglion cell-inner plexiform layer (GCIPL) thickness after cataract surgery using spectral-domain optical coherence tomography (OCT).
METHODS
Forty-three eyes of 33 patients, who underwent cataract surgery were imaged with spectral-domain OCT before and after surgery to measure peripapillary retinal nerve fiber layer (RNFL) and GCIPL thickness, signal strength (SS), quadrant, 12 clock-hour RNFL thickness and sectoral GCIPL thickness.
RESULTS
The postoperative SS, RNFL and GCIPL thickness were higher than before surgery (p < 0.05). Multivariate analysis showed that endothelial cell count and preoperative SS were significantly correlated with SS changes in RNFL parameters and preoperative SS was significantly correlated with SS changes in GCIPL parameters. Univariate analysis indicated that age was significantly correlated with RNFL thickness changes in RNFL parameters and no factor was correlated with GCIPL thickness in GCIPL parameters (p < 0.05).
CONCLUSIONS
Cataracts may decrease peripapillary RNFL and GCIPL thickness measurements and SS on OCT scans. Peripapillary RNFL and GCIPL thickness measurements should be interpreted with caution in eyes with significant cataracts.

Keyword

Cataract surgery; Ganglion cell-inner plexiform layer; Optical coherence tomography; Peripapillary retinal nerve fiber layer

MeSH Terms

Cataract*
Endothelial Cells
Ganglion Cysts*
Humans
Multivariate Analysis
Nerve Fibers
Retinaldehyde
Tomography, Optical Coherence*
Retinaldehyde

Figure

• 

  Figure 1. Changes of RNFL and GCIPL thickness before (A, C) and after (B, D) cataract surgery in the left eye of a 69-year-old man. Signal strength, quadrant, 12 clock-hour, average RNFL thickness, sectoral, aver-age, minimum GCIPL thickness were higher than before surgery. Color codes of 9, 11 clock-hour RNFL thickness were changed after surgery. RNFL = retinal nerve fiber layer; GCIPL = ganglion cell-inner plexiform layer; S = superior; N = nasal; I = inferior; T = temporal; OS = oculus sinister; GCL = gan-glion cell layer; IPL = inner plexiform layer.

Reference

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