J Korean Surg Soc.  2010 May;78(5):334-337. 10.4174/jkss.2010.78.5.334.

Pediatric Solitary Castleman's Disease Concurrently Arising from Neck & Axilla

• Ro HW
• Ryu HS
• Cho JS
• Park MH
• Yoon JH
• Jegal YJ
• Lee JS
• Lim HS

• KMID: 2211962
• DOI: http://doi.org/10.4174/jkss.2010.78.5.334

Abstract

Castleman's disease (CD) is an unusual benign lymphoproliferative disorder of unknown etiology and pathogenesis. It most commonly occurs in the mediastinum, but rarely in the axilla or neck. CD has been rarely reported at pediatric age in Korea. Here we report a 17-month-old male patient with histopathologically proven cervical & axillary CD of the hyline vascular type who presented with a painless axillary palpable mass and was treated with a complete excision of the neck & axilla mass without complication.

Keyword

Castlman's disease; Pediatric; Neck; Axilla

MeSH Terms

Axilla
Giant Lymph Node Hyperplasia
Humans
Infant
Korea
Lymphoproliferative Disorders
Male
Mediastinum
Neck

Figure

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  Fig. 1 Ultrasonography of the left axilla shows multiple conglomerated round hypoechogenic mass.

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  Fig. 2 Contrast enhanced CT scan of neck reveals multiple conglomerate homogeneously enhancing oval to round lymph nodes (arrowheads) in both level II and left axillary area.

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  Fig. 3 There were proliferative lymphoid follicles and hyalinized germinal center capillary proliferation and many plasma cells in interfollicular space. (A) Cervical lymph node (LN) (H&E stain, ×100). (B) Cervical LN (H&E stain, ×400). (C) Axillary LN (H&E stain, ×100). (D) Cervical LN (H&E stain, ×400).

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