J Korean Ophthalmol Soc.  2007 Oct;48(10):1415-1418. 10.3341/jkos.2007.48.10.1415.

A Case of Fungal Keratitis as a Complication of Orthokeratology Contact Lens

• Lee JK
• Lee JE
• Lee JS

• KMID: 2210997
• DOI: http://doi.org/10.3341/jkos.2007.48.10.1415

Abstract

PURPOSE: To present a case report of fungal keratitis related to prolonged overnight use of orthokeratology contact lenses.
METHODS
A 13 year-old girl presented with a corneal ulcer in her left eye refractory to antibacterial medication. She had a history of wearing orthokeratology contact lenses overnight for seven months.
RESULTS
The organism Aspergillus was isolated by corneal scraping, the contact lens itself, and from the storage case. The patient was treated with topical fluconazole and Natamycin pimaricin in addition to oral itraconazole, resulting in a resolution of the ocular lesion.
CONCLUSIONS
The risk of fungal infection as a potential complication of the use of overnight orthkeratology contact lenses should be considered when using these lenses.

Keyword

Aspergillus; Fungal keratitis; Natamycin; Orthokeratology

MeSH Terms

Adolescent
Aspergillus
Contact Lenses
Corneal Ulcer
Female
Fluconazole
Humans
Itraconazole
Keratitis*
Natamycin
Fluconazole
Itraconazole
Natamycin

Figure

• 

  Figure 1. Slitlamp view of patient's left eye shows squareshaped, 3.5×3.5 mm sized irregular corneal infiltration which is located slightly inferior to the corneal center.

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  Figure 2. Cotton blue staining of corneal scraping. Highpower photomicrograph shows hyphe elements of Aspergillus.

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  Figure 3. After 3 months, residual corneal scarring remained.

Reference

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