J Korean Surg Soc.  2003 Jan;64(1):72-76.

A Case of Malignant Fibrous Histiocytoma-like Sarcomatoid Metaplastic Carcinoma of the Breast

Affiliations
  • 1Department of Surgery, College of Medicine, Hanyang University, Seoul, Korea. pjjung@hanyang.ac.kr
  • 2Department of Pathology, College of Medicine, Hanyang University, Seoul, Korea.

Abstract

A metaplastic carcinoma of the breast (MpC) is a very rare malignant tumor accounting for fewer than 1% of all mammary tumors. MpCs are difficult to diagnose accurately and classify because of their rarity and varied histological patterns. A MpC is a histologically diverse type of malignancy in which an adenocarcinoma is found to co-exist with an admixture of spindle cells, squamous, chondroid, or bone-forming neoplastic cells. Cystic changes can be encountered in MpC, particularly in carcinoma with squamous metaplasia, but are rare in a sarcomatoid metaplastic carcinoma. We recently experienced an unusual case of a sarcomatoid metaplastic carcinoma mimicking a malignant fibrous histiocytoma of the soft tissue in a 34-year-old female, who had a breast tumor with an extensive cystic change, which was growing rapidly. Here, we report this unusual case of MpC with a review of the relevant literature.

Keyword

Breast cancer; Sarcomatoid; Metaplastic carcinoma

MeSH Terms

Adenocarcinoma
Adult
Breast Neoplasms
Breast*
Female
Histiocytoma, Malignant Fibrous
Humans
Metaplasia
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