J Korean Pediatr Soc.
1981 Sep;24(9):865-871.
Congenital Systemic Cytomegalic Inclusion Disease: An Autopsy Case Report
- Affiliations
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- 1Department of Pediatrics, Cheil Hospital, Korea.
- 2Department of Pathology, Cheil Hospital, Korea.
- 3Department of Pathology, College of Medicine, Seoul National University, Korea.
Abstract
- A case of systemic cytomegalovirus infection in a newborn baby is reported. This female baby was born after 36 weeks gestation to a 30 year-old mother who had no prenatal problem except for breech presentation and placenta previa for which Caesarian section was given. The mother has two healthy children. The clinical course of this baby was characterized by repeat spells of apnea, cyanosis and edema, that progressed to deepening jaundice and generalized petechiae. She died 58 hours after birth. A characteristic linear calcification along the ventricular wall of the brain enabled us to suggest congenital nature of cytomegalic inclusion disease in the patient. Postmortem exmaination showed numeorous cystomegalic inclusions in kidneys, pancreas, liver and thyroid. There was subependymal and periaqueductal calcification together with hydrocepalus and cerebellar hypoplasia.
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