J Korean Pediatr Soc.  1998 Jun;41(6):841-843.

A Case of Ceftriaxone-induced Pseudocholelithiasis

Affiliations
  • 1Department of Pediatrics, College of Medicine, Ulsan University, Seoul, Korea.
  • 2Department of Diagnostic Radiology, College of Medicine, Ulsan University, Seoul, Korea.

Abstract

Ceftriaxone, a third-generation cephalosporin, is a very potent, broad spectrum antibiotic commonly used in patients with meningitis, osteomyelitis, pyelonephritis, Lyme disease and many other severe infectious diseases. Up to 46% of those receiving this antibiotic develop gallbladder sludge. Most of them are asymptomatic, but a small proportion may develop right upper quadrant pain, nausea, vomiting and even cholecystitis. We report a case of ceftriaxone-induced pseudocholelithiasis in a 5-year-old boy. We also emphasize the fact that surgical interventions such as cholecystectomy is not necessary, because the condition may resolve spontaneously after cessation of the drug.

Keyword

Ceftriaxone; Biliary Pseudolithiasis; Pseudocholelithiasis; Gallbladder sludge

MeSH Terms

Ceftriaxone
Child, Preschool
Cholecystectomy
Cholecystitis
Communicable Diseases
Gallbladder
Humans
Lyme Disease
Male
Meningitis
Nausea
Osteomyelitis
Pyelonephritis
Sewage
Vomiting
Ceftriaxone
Sewage
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