J Korean Ophthalmol Soc.  2005 Mar;46(3):410-415.

Short-term Change in Corneal Endothelium after Iris-Fixed Phakic Intraocular Lens Insertion

• Lee ES
• Cho YJ
• Kim EK

Abstract

PURPOSE
To investigate endothelial change in phakic eyes implanted with Artisan phakic IOL inserts and to identify the associated factors. METHODS: We prospectively examined the endothelial change in 11 phakic eyes implanted with Artisan phakic IOL inserts. Noncontact specular microscopy was performed preoperatively, and at 1 week and 1 month postoperatively. RESULTS: The mean endothelial cell loss was 3.57% at 1 week, and 4.69% at 1 month. There was a statistically significant decrease in endothelial cell density and an increase in pleomorphism and polymegathism of the cells after the surgery which indicate cellular damage (p<0.05). There were no statistically significant changes in endothelial cell density, shape, or size between 1 week and 1 month postoperatively (p>0.05). No correlation was observed between cell loss and corneal curvature, critical distance, IOL optic size, IOL diopter, or serial order of the operation. However, there was significant negative correlation (R=-7.600; p>0.05) between cell loss and anterior chamber depth. CONCLUSIONS: Endothelial damage occurred primarily during the surgical procedure and special attention should be given to patients with shallow anterior chamber depth for iris-fixed phakic IOL inserts to avoid unintended endothelial damage.

Keyword

Corneal endothelial cell; Iris-fixed phakic intraocular lens; Myopia

MeSH Terms

Anterior Chamber
Endothelial Cells
Endothelium, Corneal*
Humans
Microscopy
Myopia
Phakic Intraocular Lenses*
Prospective Studies