J Korean Pediatr Soc.
2002 Sep;45(9):1165-1169.
A Case of Satoyoshi Syndrome Presented with Progressive Muscular Spasm and Alopecia
- Affiliations
-
- 1Department of Pediatrics, Chonnam National University Medical School, Gwangju, Korea. kimbj@chonnam.ac.kr
- 2Department of Dermatology, Chonnam National University Medical School, Gwangju, Korea.
Abstract
- Satoyoshi syndrome(generalized Komuragaeri disease) is a rare disorder of unknown cause, characterized by progressive, painful, intermittent muscle spasms and alopecia. Endocrinopathy with amenorrhea, secondary skeletal abnormalities, and diarrhea or unusual malabsorption are frequently seen. It seems that autoimmunity may play a role in its pathogenesis. We report a 13-year-old girl with characteristic manifestations of the syndrome. She was treated with intravenous gammaglobulin and Prednisolone. Painful muscle cramps were gradually improved, but the scalp condition did not change. Satoyoshi syndrome should be considered in children with unexplained muscle spasms and alopecia.
