J Korean Ophthalmol Soc.  2002 Sep;43(9):1789-1796.

Kimura's Disease Involving The Eyelid and Orbit

• Chung DH
• Kim BJ
• Kim YD

Abstract

PURPOSE: Kimura's disease is a benign slow-growing subcutaneous tumor, which is manifested clinically by one or more inflammatory nodules invading mainly the head and neck. Orbital, eyelid and lacrimal involvement by Kimura disease is rare. We report two cases of Kimura's disease involving the orbit and eyelid , which has not been reported in korea.
METHODS
A 16-year-old male patient presented with the chief complaint of upper eyelid swelling and ptosis that was first noticed 15 years ago. Another 16-year-old male patient visited our clinic with multiple nodules involving the head, neck, left upper arm, and the both upper eyelids . Ocular examination of case.1 revealed upper eyelid swelling and redness, painless nodule, and ptosis. In case 1. patient, Orbital MRI scan showed thickening of the superior, inferior, medial rectus muscle, levator palpebrae muscle, and a well-demarcated homogenous mass in the superonasal portion of the left orbit.
RESULTS
Histopathologically, the lesions were characterized by lymphoid follicles, infiltration of many eosinophils, lymphocytes, abnormal capillary proliferation and fibrosis. Laboratory findings definitely revealed peripheral blood eosinophilia in both patients.
CONCLUSIONS
Kimura's disease should be suspected and considered in the differential diagnosis for the patients with the eyelid swelling and mass.

Keyword

Eosinophilia; Eyelid swelling; Kimura's disease; Painless nodule; Ptosis

MeSH Terms

Adolescent
Angiolymphoid Hyperplasia with Eosinophilia
Arm
Capillaries
Diagnosis, Differential
Eosinophilia
Eosinophils
Eyelids*
Fibrosis
Head
Humans
Korea
Lymphocytes
Magnetic Resonance Imaging
Male
Neck
Orbit*