J Korean Ophthalmol Soc.  1999 Oct;40(10):2766-2772.

The Comparison of the Anti-inflammatory Effect be tween Nonsteroidal Anti-inflammatory and Steroid Eye Drops in Cataract Surgery

• Doh HJ
• Choi YK
• Kim MS
• Kim JH

Abstract

Usually steroid is the first choice drug in cataract surgery because of variety and good effect, but we need a new drug because of side effects such as glaucoma and infection. We selected 68 eyes of 63 patients for cataract surgery and divided two groups. One group used steroid [37 eyes] and the other did nonsteroidal anti-inflammatory drug [NSAID] [31 eyes] preoperatively for 2 months. We compared the changes of pupil size during the operation, corrected visual acuity, anti-inflammatory reaction, corneal thickness, intraocular pressure, conjunctival inflammation and other adverse reactions after surgery. The results were not significantly different between the two groups except the change of pupil size during operation. The change of pupil size from preop-erative states to end of operation in NSAID group was from 8.64 +/-0.64mm to 7.73 +/-1.05mm and that of steroid group was from 8.55 +/-0.83mm to 6.98 +/-1.60 mm. The results were significantly different between the two groups. Therefore, NSAID may be effective and safe as an anti-inflammatory drug and as a miosis inhibitor in cataract surgery.

Keyword

Nonsteroidal anti-inflammatory drug; Cataract surgery

MeSH Terms

Cataract*
Glaucoma
Humans
Inflammation
Intraocular Pressure
Miosis
Ophthalmic Solutions*
Pupil
Visual Acuity
Ophthalmic Solutions