J Korean Ophthalmol Soc.
1995 Mar;36(3):525-530.
Primary antiphospholipid syndrome associated with non-ischemic central retinal vein occlusion
- Affiliations
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- 1Department of Ophthalmology, College of Medicine, Korea University, Seoul, Korea.
- 2Department of Internal Medicine, College of Medicine, Korea University, Seoul, Korea.
Abstract
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Antiphospholipid syndrome is a disease producing vascular thrombosis with antiphospholipid antibody and usually associated with systemic lupus erythematosus. It is called primary antiphospholipid syndrome(PAPS) if it does not have the clinical features of collagen vascular disorder. Ocular manifestations of antiphospholipid syndrome include retinal vascular disorder, anterior ischemic optic neuropathy, and amaurosis fugax. Ocular manifestations are much less common in primary antiphospholiped syndrme than antiphospholipid syndrome associated with systemic lupus erythematosus. We experienced two cases of non-ischemic central retinal vein occlusion which were associated with primary anti phospholipid syndrome in two female patients, who complained sudden decrease of visual acuity in one eye. We report the cases with review of the literatures.