J Korean Ophthalmol Soc.
1988 Dec;29(6):1131-1139.
A Case of Severe Ocular Myasthenia Gravis that Developed Total External Ophthalmoplegia
- Affiliations
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- 1Department of Ophthalmology, Wonju College of Medicine, Yonsei University, Wonju, Korea.
Abstract
- Myasthenia gravis is a chronic disease characterized by voluntary muscle weakness and fatigue. Myasthenia gravis was first described by Thomas Willis in 1672. The etiology of myasthenia gravis is not clarified but recently it has been suggested that it is an autoimmune disease. Ocular myasthenia gravis is characterized clinically by blepharoptosis and external ophthalmopleia. The illness has a tendency to exacerbation and spontaneous remission. The authors observed a case of severe ocular myasthenia gravis which had developed total external ophthalmoplegia. And we reviewed the literature of recent years related to myasthenia gravis, particulary for its etiology, clinical course, pathology, diagnosi, treatment, and prognosis.
