J Korean Ophthalmol Soc.
1986 Aug;27(4):587-590.
The Effect of Diabetes Mellitus on the Amount of Human Cataractous Lens Protein
- Affiliations
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- 1Department of Ophthalmology, College of Medicine, Seoul National University, Korea.
Abstract
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We have quantified human cataractous lens protein in 10 diabetic patients and 10 non-diabetic patients by using a colorimetric method, to investigate the effect of diabetes mellitus on the amount of human cataractous lens prorein. Protein amount of the diabetic lens cortex(1.26 +/- 0.48mg/ml) was significantly smaller than that of the non-diabetic lens cortex(1.83 +/- 0.44mg/ml) (t=3.36, p<0.005). On the other hand, protein amount of the lens nucleus did not reveal a significant difference between the diabetic(3.06 +/- 0.61mg/ml) and the non-diabetic(3.08 +/- 0.96mg/ml) cataract patients.