J Korean Soc Transplant.
2015 Mar;29(1):1-8. 10.4285/jkstn.2015.29.1.1.
Immunosuppression in Pediatric Kidney Transplant Patients
- Affiliations
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- 1Department of Surgery, Seoul National University College of Medicine, Seoul, Korea. jwhamd@snu.ac.kr
- 2Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea.
- KMID: 2202557
- DOI: http://doi.org/10.4285/jkstn.2015.29.1.1
Abstract
- Over the last two decades, newer immunosuppressive agents have been introduced in the field of solid organ transplantation, and provided better graft and patient outcome. A wider range of immunosuppressants available to transplant physicians have resulted in improved therapeutic strategies to offer the combinations of medications with non-overlapping toxicities and more suitable immunosuppression. However, only a few clinical trials of new immunosuppressants have been conducted in pediatric patients. This review will discuss the cutting-edge strategy of immunosuppression in children and the current status of new immunosuppressive agents in pre- and post-transplant management to prevent kidney allograft rejection.
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