J Korean Rheum Assoc.  1999 Jun;6(2):197-201.

A case of Diffuse Idiopathic Skeletal Hyperostosis (DISH) Presented with Idiopathic Hypoparathyroidism and Diabetes Mellitus

Affiliations
  • 1Department of Medicine, university of Ulsan, Asan Medical Center, Seoul, Korea.
  • 2Department of Radiology, university of Ulsan, Asan Medical Center, Seoul, Korea.

Abstract

Diffuse Idiopathic Skeletal Hyperostosis (DISH) is a skeletal disease characterized by ligamentous ossification of the anterolateral side of the spine. Paravertebral and ligamentous ossification appears to be an usual complication of hypoparathyroidism. Diabetes Mellitus has often been mentioned in associated with DISH. The patient was presented with back pain, stiffness and intermittent numbness of hands and feet. Spine X-ray showed extensive ligamentous ossification of the anterolateral side of the spine with normal disc space height. Sacroiliac joints are normal. Increased bone mineral density of the L-spine and femur neck was observed, as well. Hypocalcemia, hyperphophatemia and low intact parathyroid hormone level were detected. Postprandial sugar were elevated. HLA B27 was negative.

Keyword

DISH; Diabetes mellitus; Idiopathic hypoparathyroidism

MeSH Terms

Back Pain
Bone Density
Diabetes Mellitus*
Femur Neck
Foot
Hand
Humans
Hyperostosis, Diffuse Idiopathic Skeletal*
Hypesthesia
Hypocalcemia
Hypoparathyroidism*
Ligaments
Parathyroid Hormone
Sacroiliac Joint
Spine
Parathyroid Hormone
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