J Korean Rheum Assoc.  2004 Mar;11(1):61-65.

A Case of Primary Sjogren's Syndrome with Protein-losing Enteropathy

Affiliations
  • 1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. ysong@snu.ac.kr

Abstract

Protein-losing enteropathy is a rare complication of autoimmune diseases. We report a case of primary Sjogren's syndrome with protein-losing enteropathy in 50-year-old female who complained of generalized edema. Protein-losing enteropathy of the small intestine was demonstrated by Tc-99m labeled albumin abdominal scintigraphy. Duodenal biopsies showed chronic inflammatory cell infiltration without lymphangiectasis or vasculitis. The patient received oral prednisolone (60 mg/day) for 4 weeks with subsequent clinical improvement. Primary Sjogren's syndrome or other autoimmune diseases should be considered in cases of protein-losing enteropathy.

Keyword

Sjogren's syndrome; Protein-losing enteropathy; Prednisolone

MeSH Terms

Autoimmune Diseases
Biopsy
Edema
Female
Humans
Intestine, Small
Lymphangiectasis
Middle Aged
Prednisolone
Protein-Losing Enteropathies*
Radionuclide Imaging
Sjogren's Syndrome*
Vasculitis
Prednisolone
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