J Korean Soc Transplant.  2008 Jun;22(1):135-137.

A Case of Invasive Aspergillosis in Transplanted Kidney and Perirenal Area

• Na HH
• Hong SW
• Kim MC
• Kang YK
• Yoon YC
• Koh HI

Abstract

Recently, the incidence of fungal infection increases because of immunosuppressive therapy and chemotherapy. In immunosuppressed transplant recipients, Aspergillus can be a dangerous pathogen, capable of inducing fulminant clinical disease. Invasive fungal infections are life-threatening complications in solid-organ transplantation. Although the rate of fungal infections in transplant recipients is lower than that of other infections, the mortality rate is higher. A 34 year-old male was admitted to our hospital with fever and gross hematuria. He had received renal transplantation 2 years ago and had been transferred the other hospital 1 month ago. Initial laboratory data evaluation showed a pancytopenia and azotemia. We thought that pancytopenia was caused by immunosuppressive agents and infection. The patient was treated with antibiotics but fever was not subsided. After 4 days, he complained of transplant site pain and tenderness to percussion. A percutaneous renal biopsy was performed. Microscopic examination showed invasive aspergillosis in transplanted kidney and perirenal area. We removed the transplanted kidney and perirenal tissue, and prescribed antifungal agents for 3 months.

Keyword

Aspergillus; Invasive aspersillosis; Kidney transplantation

MeSH Terms

Anti-Bacterial Agents
Antifungal Agents
Aspergillosis
Aspergillus
Azotemia
Biopsy
Fever
Hematuria
Humans
Immunosuppressive Agents
Incidence
Kidney
Kidney Transplantation
Male
Pancytopenia
Percussion
Transplants
Anti-Bacterial Agents
Antifungal Agents
Immunosuppressive Agents