Korean J Nephrol.  2010 Mar;29(2):300-304.

A Case of Invasive Aspergillosis Limited to Renal Allograft

Affiliations
  • 1Department of Internal Medicine, Masan Samsung Hospital, Sungkyunkwan University School of Medicine, Korea. fivegentle@naver.com

Abstract

Though the development of immunosuppressive agents has increased the survival rate of transplanted kidneys, the opportunistic infection has increased in transplant recipients. Aspergillus may cause invasive aspergillosis via sino-pulmonary route in immunocompromized patients. We report a rare case of invasive aspergillosis of a transplanted kidney without having disseminated disease. A 41 year-old female, who underwent cadaveric renal transplantation 10 months ago, presented with diarrhea and anemia. Ultrasound examination and CT scan revealed an abscess lesion in the transplanted kidney. Surgical curettage and percutaneous drainage were performed. Because, microscopic examination demonstrated fungal hyphae consistent with Aspergillus species, antifungal agents were prescribed. Later, partial transplant nephrectomy and embolization of the remnant kidney were performed.

Keyword

Aspergillus; Invasive aspergillosis; Renal/kidney transplantation

MeSH Terms

Abscess
Anemia
Antifungal Agents
Aspergillosis
Aspergillus
Cadaver
Curettage
Diarrhea
Drainage
Female
Humans
Hyphae
Immunosuppressive Agents
Kidney
Kidney Transplantation
Nephrectomy
Opportunistic Infections
Survival Rate
Transplantation, Homologous
Transplants
Antifungal Agents
Immunosuppressive Agents
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