J Korean Radiol Soc.  1994 Jul;31(1):157-163.

Efficacy of IVIRI for Therapeutic Evaluation of Bone Lymphoma

• Kim YC
• Kim BS
• Chung JK
• Kim KI
• Park JM
• Lee SH
• Moon TY
• Kim EE

Abstract

PURPOSE
A retrospective study was performed to assess the efficacy of MRI in evaluation of therapeutic response of bone lymphoma.
MATERIALS AND METHODS
We reviewed 17 cases of bone lymphoma on MRI that were follow-up studies during or after therapy. Among them, the cases with contrast study during therapy were 5, and those after therapy were 6. The four findings of follow-up MRI considered representative of improvement of bone lymphoma were the decreased size of tumor mass, the decreased signal intensity on T2-weighted images, the increased signal intensity of the tumor on T1 -weighted images, and the decreased or absent enhancement of post-contrast T1 -weighted images.
RESULTS
The findings of improvement on T1 and T2-weighted images were shown in 50%(7/14) during therapy and 85.7%(12/14) after therapy. Those On post-contrast T1 -weighted images were shown in 20%(1/5) during therapy and 50%(3/6) after therapy.
CONCLUSION
On MRI, both findings of the decreased signal intensity on T2-weighted images and the increased signal intensity of on T1 -weighted images of the tumor were significant in evaluating therapeutic response of bone lymphoma.

MeSH Terms

Follow-Up Studies
Lymphoma*
Magnetic Resonance Imaging
Retrospective Studies