J Korean Radiol Soc.  1998 Oct;39(4):709-715. 10.3348/jkrs.1998.39.4.709.

Dual Phase CT Hepatic Arteriography in the Evaluation of Hypervascular Hepatocellular Carcinoma

• Bae SH
• Kim HC
• Choi CS
• Shim JE
• Yoon DY
• Han SW
• Seo YL
• Hur H

• KMID: 2201220
• DOI: http://doi.org/10.3348/jkrs.1998.39.4.709

Abstract

PURPOSE: To assess the diagnostic accuracy of dual-phase computed tomography during hepaticarteriography(CTHA) in depicting hypervascular hepatocellular carcinoma.
MATERIALS AND METHODS
Forty patientswith hepatocellular carcinoma underwent dual-phase CTHA. First-phase data was obtained 6 seconds after contrastmedia was injected into the common hepatic artery, while second-phase data was obtained 35-40 seconds later.Lipiodol CT was performed 10-17 days after 2mL of lipiodol was injected into the proper hepatic artery. As agold-standard of 172 lipiodol-uptaken nodules seen on lipiodol CT, the detectability and positive predictive valueof the first and second phases, and the simultaneous interpretation of both phases, were analysed.
RESULTS
Allnodules were detected by first-phase CTHA, 162 (94%) by second-phase CTHA, and 170 (99%) by simultaneousinterpretation of both phases. The detection sensitivities of first-phase CTHA and simultaneous interpretation ofboth phases were statistically superior to that of second-phase CTHA. Positive predictive values were 87% withfirst-phase CTHA, 96% with second-phase CTHA, and 97% with simultaneous interpretation of both phases.
CONCLUSION
Dual-phase CTHA was useful for increasing detectability and accuracy in the diagnosis of hypervascularhepatocellular carcinoma.

Keyword

Computed tomography(CT), comparative studies; Hepatic arteries, CT; Liver neoplasms, diagnosis

MeSH Terms

Angiography*
Carcinoma, Hepatocellular*
Diagnosis
Ethiodized Oil
Hepatic Artery
Ethiodized Oil