J Menopausal Med.  2015 Dec;21(3):155-159. 10.6118/jmm.2015.21.3.155.

Ovarian Cavernous Hemangioma Presenting as a Large Growing Mass in a Postmenopausal Woman: A Case Report and Review of the Literature

Affiliations
  • 1Department of Obstetrics and Gynecology, Pusan National University School of Medicine, Busan, Korea. ghkim@pusan.ac.kr
  • 2Department of Radiology, Pusan National University School of Medicine, Busan, Korea.
  • 3Department of Pathology, Pusan National University School of Medicine, Busan, Korea.
  • 4Department of Obstetrics and Gynecology, Kosin University College of Medicine, Busan, Korea.

Abstract

Ovarian hemangiomas are usually of the cavernous type, and are rarely encountered. A 73-year-old woman presented with lower abdominal discomfort. Subsequent physical examination depicted a palpable mass in the lower abdomen. Abdominopelvic computed tomography (CT) revealed a well-circumscribed mass with thin septa measuring 12.1 x 9.0 cm in the right ovary. Levels of the tumor markers cancer antigen (CA)-125 and CA 19-9 were within the normal range. At laparoscopy, the tumor was found to be confined to the right ovary and to have a smooth surface. The final histopathological result was ovarian cavernous hemangioma. Microscopically, the mass consisted of multiple, dilated, blood-filled vascular channels separated by loose connective tissue, and all were lined by a single layer of flattened endothelium. The authors present a case of ovarian cavernous hemangioma presenting as a large growing mass in a postmenopausal woman and review previously published literature.

Keyword

Hemangioma; Ovary; Postmenopause

MeSH Terms

Abdomen
Aged
Connective Tissue
Endothelium
Female
Hemangioma
Hemangioma, Cavernous*
Humans
Laparoscopy
Ovary
Physical Examination
Postmenopause
Reference Values
Biomarkers, Tumor

Figure

  • Fig. 1 (A) Contrast enhanced computed tomography (CT) image showing a 6.4 cm, well-defined, thin-walled cyst with thin septa in the right ovary. (B) Follow-up CT image obtained 5 years later showing an increase in mass size to a maximal diameter of 12.1 cm.

  • Fig. 2 Gross findings of the ovarian mass. The multiloculated cystic lesion contained occasional blood clots (▸). The remnant ovary is also seen in left lower part (arrow).

  • Fig. 3 Microscopic findings of ovarian hemangioma. (A) The mass possessed numerous, dilated vascular spaces adjacent to remnant ovarian tissue on the left side (*) (hematoxylin & eosin [H & E] ×40). (B) Vascular spaces were lined by flattened endothelial cells without cytologic atypia (H & E ×200).


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