J Korean Soc Endocrinol.
2004 Feb;19(1):76-81.
A Case of Ectopic ACTH Syndrome Associated with Bronchial Carcinoid
- Affiliations
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- 1Department of Internal Medicine, College of Medicine, Pusan National University, Pusan, Korea.
- 2Department of Thoracic and cardiovascular Surgery, College of Medicine, Pusan National University, Pusan, Korea.
Abstract
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Fifteen percent of patients with Cushing's syndrome could be accompanied with nonpituitary tumors that secrets ACTH-the ectopic ACTH syndrome. Among them, bronchial carcinoid is one of the rare causes of the ectopic ACTH syndrome. We experienced a 60-year-old woman who showed conditions of weight gain, generalized edema, hypokalemia, diabetes mellitus, and right middle lung mass. Histologically, the tumor was diagnosed with bronchial carcinoid and was confirmed as an ectopic ACTH syndrome through immunohistochemical staining of ACTH. After resection of the lung mass, blood sugar, electrolytes, generalized weakness, and blood pressure improved.