J Korean Soc Transplant.  2001 Dec;15(2):256-258.

Malakoplakia in a Renal Allograft: A case report

• Kim SE
• Noh TW
• Kown KW
• Jeong HJ
• Kim YS
• Kim SI
• Park KI

Abstract

Malakoplakia is a rare inflammatory disease which usually involves the lower urinary tracts, especially in immunocompromised patients. The characteristic feature is parenchymal infiltration by macrophages, known as von Hansemann cells, and intra- or extracytoplasmic Michaelis-Gutmann bodies. We report a case of renal malakoplakia in a renal allograft patient. Renal allograft biopsy was performed 1.5 years posttransplantation under the impression of chronic rejection. By light microscopy, inflammatory infiltrate composed of many macrophages and Michaelis-Gutmann bodies were present in the renal medulla and accompanied by moderate tubular atrophy and interstitial fibrosis. (J Korean Soc Transplant 2001;15:256-258)

Keyword

Renal transplantation; Malakoplakia

MeSH Terms

Allografts*
Atrophy
Biopsy
Fibrosis
Humans
Immunocompromised Host
Kidney Transplantation
Macrophages
Malacoplakia*
Microscopy
Urinary Tract