J Korean Soc Pediatr Nephrol.
2008 Oct;12(2):213-220.
Peritoneal Dialysis Associated Peritonitis and Empirical Antibiotics Therapy in Korean Children with Chronic Renal Failure
- Affiliations
-
- 1Department of Pediatrics, Samsung Medical Center Sungkyunkwan University School of Medicine, Seoul, Korea. kyunghoon.paik@samsung.com
Abstract
-
PURPOSE: This study aims to verify the effectiveness of initial empirical antibiotic choice recommended by the International Society for Peritoneal Dialysis(ISPD) guide among Korean children.
METHODS
We have collected data on peritonitis from January 2001 to December 2007 in Samsung Medical Center.
RESULTS
Of the 42 patients, 48 episodes of peritonitis had occurred in 21 patients. The rate of peritonitis was one episode over 35.3 patient-months. Mean dialysis duration before peritonitis was 18.06+/-15.81 months. Gram-positive organisms accounted for 58.3% of all episodes. Of the gram-positive organisms, the most common pathogen was Staphylococcus aureus(29.2 %), the next common pathogens were Coagulase negative staphylococcus(14.6%) and Streptococcus species(6.3%). 35.7% of gram-positive pathogens were resistant to 1st cephalosporin. However, in patients younger than 4 years old, 50% of gram-positive pathogens were resistant to 1st generation cephalosporin. 10 episodes of peritonitis were methicillin-resistant and were treated by vancomycin. Of the gram-negative organisms, E. coli was the most common (8.3%). 64.8% of all pathogens were sensitive to cephalothin or ceftazidime.
CONCLUSION
The empirical therapy with 1st generation cephalosporin and ceftazidime can be also effective to peritoneal dialysis associated peritonitis in Korean children. However, in patients younger than 4 years old, glycopeptide should be considered as the first empirical therapy in Korean children.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Complications of Continuous Ambulatory Peritoneal Dialysis in Children
- A Rare Cause of Automated Peritoneal Dialysis-Related Peritonitis: Aeromonas caviae
- A Case of Fulminant Sclerosing Peritonitis Presented Like Acute Culture-Negative Peritonitis and Successfully Treated with Corticosteroid Therapy
- Peritoneal dialysis in children and adolescents
- New dialysis treatment options for patients with end-stage chronic kidney disease
