J Korean Soc Pediatr Endocrinol.  2002 Jun;7(1):122-127.

A Case of Cerebral Gigantism(Sotos Syndrome)

• Kim SB
• Yang S
• Kim HD
• Oh PS
• Cha JK
• Shin JH

Abstract

Cerebral gigantism(Sotos syndrome) is a growth disorder that consists of large size at birth, rapid early growth rate with accompanying advanced bone age, acromegalic features, and developmental delay. Clumsiness in the absence of other abnormal neurologic findings is common. The cause is unknown. We report here a case of 238/12-year-old Sotos syndrome with final adult height above 97 percentile, abnormal brain MRI findings(large ventricles, prominent trigone, prominent occipital horn & thining of corpus callosum), clumsiness, and some behavioral problems.

Keyword

Cerebral Gigantism; Sotos syndrome

MeSH Terms

Adult
Animals
Brain
Growth Disorders
Horns
Humans
Magnetic Resonance Imaging
Neurologic Manifestations
Parturition
Sotos Syndrome