J Korean Radiol Soc.  1990 Apr;26(2):358-364. 10.3348/jkrs.1990.26.2.358.

Paraneoplastic precocious puberty and excessively rapid somatic growth associated with pediatric malignanthepatic tumor: A report of 2 cases

• Kim OH
• Bahk YW

• KMID: 2358954
• DOI: http://doi.org/10.3348/jkrs.1990.26.2.358

Abstract

Sexual precocity in a 28-months-old boy and markedly accelerated skeletal growth with large body in a 5 years and 5 months-old-girl are reported. The former resulted from human chorionic gonadotropin-producing hepatoblastomaand the latter from cerebral gigantism assocaited with hepatoma,These two different disorders are discussed on thecommon basis of rare association of malignant hepatic tumors with precocious sexual and/or somatic growth. Theclinical manifestations, chemical abnormalities, and the radiologic findings are presented with a breif review ofthe literature.

MeSH Terms

Chorion
Humans
Male
Puberty, Precocious*
Sotos Syndrome