J Korean Soc Pediatr Endocrinol.  2003 Jun;8(1):87-90.

Giant Follicular Ovarian Cyst with Torsion in Juvenile Primary Hypothyroidism

• Lee JW
• Kim HJ
• Kim HS

Abstract

Multicystic ovary was first described by Silver in 1958 as a rare case feature of acquired primary hypothyroidism. In 1980, Lindsay reported four girls with hypothyroidism associated with multicystic ovary diagnosed by pelvic ultrasonography. The mechanism of ovarian cyst formation and pseudoprecocious puberty in severe hypothyroidism in childhood are unknown. Increased ovarian sensitivity to GnRH and increased TSH level which acts on FSH receptor is one of the mechanism explained. We report a case of a girl with primary hypothyroidism presented with pseudoprecocious puberty and giant follicular ovarian cyst with torsion.

Keyword

Ovarian cyst; Hypothyroidism; Precocoius puberty

MeSH Terms

Adolescent
Female
Gonadotropin-Releasing Hormone
Humans
Hypothyroidism*
Ovarian Cysts*
Ovary
Puberty
Receptors, FSH
Silver
Ultrasonography
Gonadotropin-Releasing Hormone
Receptors, FSH
Silver