J Korean Neurol Assoc.  2009 Nov;27(4):393-397.

Left Subcortical Infarction Presenting Pure Agraphia

Affiliations
  • 1Department of Neurology, Soonchunhyang University Bucheon Hospital,Bucheon, Korea. sapark@schbc.ac.kr
  • 2Department of Physical Medicine and Rehabilitation, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.

Abstract

We report a man who exhibited pure agraphia after suffering a left subcortical infarction involving part of the thalamus and the basal ganglia. His writing difficulty was characterized by stopping, letter omission, and substitution in spontaneous writing and writing to dictation, but he was able to copy normally. Decreased perfusion in the left frontal lobe and temporal cortex was noted on brain single-photon-emission computed tomography . This patient's agraphia persisted at follow-up 52 days later. We suggest that the subcortical lesion in this patient caused pure agraphia secondary to diaschisis of the interconnected cortical area.

Keyword

Agraphia; Diaschisis; Infarction

MeSH Terms

Agraphia
Basal Ganglia
Brain
Cerebral Infarction
Coat Protein Complex I
Follow-Up Studies
Frontal Lobe
Humans
Infarction
Perfusion
Stress, Psychological
Thalamus
Writing
Coat Protein Complex I
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