J Korean Soc Emerg Med.  2016 Feb;27(1):61-68. 10.0000/jksem.2016.27.1.61.

Blood Lipid Profile as a Prognostic Factor in Patients with Organophosphate Poisoning

• Han DG
• Kim DH
• Park YJ

• KMID: 2191638
• DOI: http://doi.org/10.0000/jksem.2016.27.1.61

Abstract

PURPOSE
The purpose of this study is to compare clinical outcomes with blood lipids level and lipid solubility of organophosphate-poisoned patients.
METHODS
Data from 88 patients who visited the emergency room from January 2008 to July 2014 were analyzed. This study was conducted retrospectively using blood test results and progress notes. The contents of data included the type of organophosphate herbicide, ingesting dose, vital signs on emergency room, blood lipids level, electrocardiographic finding, and hospital course. For lipid solubility, octanol/water coefficient was used.
RESULTS
Among a total of 88 patients with organophosphate herbicide intoxication, 48 patients ingested high lipophilic organophosphate. There were statistically significant between cholesterol and duration of ventilator care. And there was a trend toward significance between cholesterol and intensive care unit, total admission stay, between triglyceride and total admission stay. As cholesterol and triglyceride level of patient was higher, the prognosis was worse.
CONCLUSION
In this study, blood cholesterol and triglyceride levels in high lipophilic organophosphate herbicide intoxicated patients are useful predictable factors for prognosis.

Keyword

Organophosphate poisoning; Cholesterol; Triglyceride; Prognosis

MeSH Terms

Cholesterol
Electrocardiography
Emergency Service, Hospital
Hematologic Tests
Humans
Intensive Care Units
Organophosphate Poisoning*
Prognosis
Retrospective Studies
Solubility
Triglycerides
Ventilators, Mechanical
Vital Signs
Cholesterol