Keimyung Med J.  2015 Dec;34(2):108-113. 10.0000/kmj.2015.34.2.108.

Study on Current Changes of Atropine Regimen in Organophosphate Pesticides Poisoning

• Kim MS
• Jin SC
• Kim SJ
• Choi WI

• KMID: 2224172
• DOI: http://doi.org/10.0000/kmj.2015.34.2.108

Abstract

Appropriate early atropinization is important for the recovery and prognosis of the organophosphate pesticides poisoning patient. However, recommended guidelines of atropine regimen in the treatment of organophosphate pesticides poisoning is not present in Korea. The authors analyzed the domestic literatures and books to investigate a trend of the regimen of atropine for organophosphate pesticides poisoning. We found 11 papers and 6 books about organophosphate pesticides poisoning that published in Korea. Then calculates elapsed time for atropinization by the each regimen of atropine. References recommendations varied markedly - atropinization of an average patient, requiring the mean dose of 23.4 mg, would have taken 15 to 432 minutes; atropinization of a very ill patient, requiring maximum dose of 75 mg, would have taken 20 to 1,385 min, Recently, it suggested atropine regimen that doubling the dose for organophosphate pesticides poisoning in Korea. So it needs to study for ensure a higher validity and application of organophosphate pesticides poisoning patients.

Keyword

Antidote; Atropine; Organophosphate

MeSH Terms

Atropine*
Humans
Korea
Pesticides*
Poisoning*
Prognosis
Atropine
Pesticides