J Korean Med Assoc.  2011 Jun;54(6):594-603. 10.5124/jkma.2011.54.6.594.

Wound coverage using advanced technology in Korea

• Han SK
• You HJ

• KMID: 2190739
• DOI: http://doi.org/10.5124/jkma.2011.54.6.594

Abstract

The purpose of this article is to outline a variety of wound coverage methods, so that general practitioners can modify their approach to wound healing and possibly incorporate this relevant information into their practice. The article starts with an update on the role of dressing materials in wound healing. It provides a balanced view of what is currently available in Korea. The use of dermal templates has helped in the coverage of wounds that in the past would have required complex surgical solutions. Growth factors and cell therapy provide many of the missing ingredients to jumpstart the wound so that it can go on to heal successfully. The negative pressure therapy, the hydrostatic pressure and/or ultrasonic therapy, and the hyperbaric oxygen therapy also help in healing wounds. Many of these products were introduced recently, and our understanding of how to use them with greater effectiveness has grown. According to the development of bioengineering techniques, advanced dressing materials, growth factors, cell therapy, etc has been introduced for clinical use. Using those materials, the wound coverage can more effective with better results.

Keyword

Wound healing; Dressing; Dermal template; Growth factor; Cell therapy

MeSH Terms

Bandages
Bioengineering
General Practitioners
Humans
Hydrostatic Pressure
Hyperbaric Oxygenation
Intercellular Signaling Peptides and Proteins
Korea
Tissue Therapy
Ultrasonic Therapy
Wound Healing
Intercellular Signaling Peptides and Proteins

Figure

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  Figure 1 Restoration of a facial defect by using an artificial dermis graft. Immediately (A) and 3 weeks after the graft (B).

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  Figure 2 Restoration of a facial defect by using an autogenous dermis graft. Preoperative (A), 1 month (B), and 1 year (C) after the graft.

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  Figure 3 Restoration of a facial defect by using a tissue-engineered dermis graft (fibroblast-hyaluronic acid complex). Immediately (A) and 1 year (B) after the graft.

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  Figure 4 A man with chronic non-healing diabetic ulcer on dorsal forefoot of 12 week duration. Pre-operative view (A). Immediately after a graft of stromal vascular fraction (SVF) cells derived from adipose tissue (B). One (C), 2 (D), and 4 (E) weeks after the SVF cell graft. Five weeks after treatment (F), the wound was successfully closed.

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  Figure 5 A man with chronic non-healing diabetic ulcer of 6 month duration. The wound healed after 7 weeks treated by blood bank platelet concentrates.

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  Figure 6 An 70-year-old man's non-healing lower leg ulcer of 6 week duration. Preoperative view (A). One (B) and 4 (C) weeks after bone marrow stromal cell therapy. The wound was closed by a skin graft (D).

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