J Korean Neurosurg Soc.
2007 Aug;42(2):149-152.
Primary Cerebellar Hodgkin's Lymphoma
- Affiliations
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- 1Department of Neurosurgery, College of Medicine, Brain Tumor Institute Dong-A University, Busan, Korea. kukim@donga.ac.kr
- 2Department of Pathology, College of Medicine, Brain Tumor Institute Dong-A University, Busan, Korea.
- 3Department of Diagnostic Radiology, Brain Tumor Institute College of Medicine, Dong-A University, Busan, Korea.
- 4Department of Onco-radiology, Brain Tumor Institute College of Medicine, Dong-A University, Busan, Korea.
Abstract
- Authors report a very rare case of primary Hodgkin's lymphoma limited to the cerebellum. A 64-year-old female patient presented with headache, nausea, and vomiting. Magnetic resonance imaging of the brain revealed a nodular enhancing mass in the left cerebellar hemisphere. Tumor was removed totally with retromastoid suboccipital approach. Diagnosis was Hodgkin's lymphoma of mixed cellularity type, consisting of a dense mixed inflammatory infiltrate containing scattered large atypical mononuclear Hodgkin cells and multinucleated Reed-Sternberg cells. Systemic work-up for the Hodgkin's lymphoma was followed with negative result. Postoperative radiation therapy was given and the patient is disease-free at 16 months after the operation.
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