J Korean Med Assoc.  2010 Apr;53(4):290-298. 10.5124/jkma.2010.53.4.290.

Screening and Diagnosis of Early Gastric Cancer

• Kim N

• KMID: 2188292
• DOI: http://doi.org/10.5124/jkma.2010.53.4.290

Abstract

Gastric cancer, the most common cancer in Korea, has come to be more frequently detected in the early stage thanks to regular endoscopy regardless of gastrointestinal symptoms. Early gastric cancer can be treated by endoscopic submucosal dissection or laparoscopic surgery, and its prognosis is very excellent. Thus, it is of an utmost importance to develop efficient screening method and set appropriate interval for the accurate diagnosis of early gastric cancer. Endoscopic screening for every two year is recommended, but the interval could be shortened in case of precancerous condition such as atrophic gastritis and intestinal metaplasia or subjects in a family with a history of gastric cancer. During the investigation, the benefit of using serology of H. pylori infection and serum pepsinogen I/II ratio of less than or equal to 3, instead of direct endoscopy, should also be considered for the selection of a high risk group of gastric cancer in Korea. Recently, appropriate screening and accurate diagnosis of early gastric cancer has become one of the most important issues.

Keyword

Gastric cancer; Early stage; Screening; Diagnosis; Endoscopy

MeSH Terms

Endoscopy
Gastritis, Atrophic
Humans
Korea
Laparoscopy
Mass Screening
Metaplasia
Pepsinogen A
Precancerous Conditions
Prognosis
Stomach Neoplasms
Pepsinogen A

Figure

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  Figure 1 Comparison of seroprevalence of H. pylori between 1998 and 2005 (19). *P < 0.05

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  Figure 2 Subtypes of early gastric cancer. Type I, protruded type; Type IIa, superficial elevated type; Type IIb, flat type; Type IIc superficial depressed type; Type III, excavated type.

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